Progresses on active targeting liposome drug delivery systems for tumor therapy / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 633-638, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-939632
ABSTRACT
Liposome is an ideal drug carrier with many advantages such as excellent biocompatibility, non-immunogenicity, and easy functionalization, and has been used for the clinical treatment of many diseases including tumors. For the treatment of tumors, liposome has some passive targeting capability, but the passive targeting effect alone is very limited in improving the drug enrichment in tumor tissues, and active targeting is an effective strategy to improve the drug enrichment. Therefore, active targeting liposome drug-carriers have been extensively studied for decades. In this paper, we review the research progresses on active targeting liposome drug-carriers based on the specific binding of the carriers to the surface of tumor cells, and summarize the opportunities, challenges and future prospects in this field.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Portadores de Fármacos
/
Sistemas de Liberação de Medicamentos
/
Lipossomos
/
Neoplasias
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2022
Tipo de documento:
Artigo
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