Survival analysis of unexpected small cell lung cancer following surgery / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 550-554, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-940921
ABSTRACT
Objective:
To investigate the survival and influencing factors of unexpected small cell lung cancer following surgery.Methods:
We respectively reviewed the clinical characters of 104 patients who underwent surgical treatment and be proved as small cell lung cancer by pathology between January 2000 to October 2020 in Chinese PLA General Hospital. Overall survival (OS) of patients was evaluated using Kaplan-Meier and Cox proportional hazards analysis.Results:
Of 104 patients, 27 cases showed central lesions, and other 77 showed peripheral nodules. The margin of nodules was smooth in 42 cases on CT imaging. The median OS was 34.3 months and 5-year OS rate was 45.8%. Postoperative 5-year OS rates for patients were 52.1%, 45.4%, and 27.8% for clinical stages Ⅰ, Ⅱ, and Ⅲ, respectively. Univariate analyses identified the age, surgical access, surgical approach, N stage, TNM stage and vascular cancer emboli were associated with OS (P<0.05). The N stage was an independent factor for the OS of patients (P<0.05).Conclusions:
Patients with unexpected SCLC, including Ⅰ, Ⅱ and part ⅢA stage have favorable outcome and can benefit from surgery and systemic postoperative treatment. Standard lobectomy plus systemic lymph node dissection is commended.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Análise de Sobrevida
/
Estudos Retrospectivos
/
Carcinoma de Pequenas Células do Pulmão
/
Neoplasias Pulmonares
/
Excisão de Linfonodo
/
Estadiamento de Neoplasias
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Oncology
Ano de publicação:
2022
Tipo de documento:
Artigo
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