Prognostic factors and efficacy of human intravenous immunoglobulin G in dogs with idiopathic immune-mediated hemolytic anemia: a retrospective study
Korean Journal of Veterinary Research
; : 139-145, 2016.
Article
em En
| WPRIM
| ID: wpr-94486
Biblioteca responsável:
WPRO
ABSTRACT
This study was conducted to determine the effect of treatment with intravenous human immunoglobulin G (hIVIgG) on outcome in dogs with idiopathic immune-mediated hemolytic anemia (IMHA), and to identify prognostic variables that determine outcome in affected dogs. Thirty-seven dogs that met the inclusion criteria were enrolled in a retrospective study. The dogs were categorized into two groups based on their having received hIVIgG. There was no significant difference in survival between the hIVIgG group and the non-hIVIgG group. Mortality during hospitalization and at 1 month, 1 year, or 2 years after discharge was not significantly different between the hIVIgG and the non-hIVIgG groups. Hemoglobinuria was significantly less prevalent in dogs that lived more than 1 year than in those who lived less than 1 year, and was less prevalent in dogs that lived more than 2 years than in those who lived less than 2 years. However, there was no difference in the presence of hemoglobinuria between dogs that lived less than 1 month and those that lived more than 1 month. Overall, there was no evidence of a beneficial effect of hIVIgG in dogs with idiopathic IMHA.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Imunoglobulina G
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Imunoglobulinas
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Estudos Retrospectivos
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Mortalidade
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Hemoglobinúria
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Hospitalização
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Anemia Hemolítica
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Anemia Hemolítica Autoimune
Tipo de estudo:
Observational_studies
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Prognostic_studies
Limite:
Animals
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Humans
Idioma:
En
Revista:
Korean Journal of Veterinary Research
Ano de publicação:
2016
Tipo de documento:
Article