Your browser doesn't support javascript.
loading
Bioactive compounds fractionated from endophyte Streptomyces SUK 08 with promising ex-vivo antimalarial activity
Asian Pacific Journal of Tropical Biomedicine ; (12): 1062-1066, 2017.
Artigo em Chinês | WPRIM | ID: wpr-950482
ABSTRACT
Objective To determine ex vivo antimalarial activity and cytotoxicity of endophytic Streptomyces SUK 08 as well as the main core structure fractionated from its crude extract. Methods The activities of SUK 08 crude extract were evaluated by using the Plasmodium lactate dehydrogenase assay and synchronization test against rodent malaria parasite Plasmodium berghei, instead of human malarial parasite Plasmodium falciparum. The cytotoxicity of the crude extract was determined by MTT assay. The crude extract was analyzed by thin-layer chromatography and gas chromatography–mass spectrophotometry. Results The ethyl acetate crude extract showed very promising antimalarial activity with IC

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2017 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2017 Tipo de documento: Artigo