Effects of arteannuin B, arteannuic acid and scopoletin on pharmacokinetics of artemisinin in mice
Asian Pacific Journal of Tropical Medicine
;
(12): 677-681, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-951372
ABSTRACT
Objective To explore the effects of arteannuin B, arteannuic acid and scopoletin on the pharmacokinetics of artemisinin in mice. Methods Artemisinin and a combination of artemisinin, arteannuin B, arteannuic acid and scopoletin were administered together to mice via oral administration. Blood samples were collected at different time intervals and pretreated by liquid–liquid extraction. The contents of four compounds in mouse plasma were determined by a validated HPLC-MS/MS method. Results Compared to single artemisinin group, the C
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Asian Pacific Journal of Tropical Medicine
Ano de publicação:
2016
Tipo de documento:
Artigo
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