MicroRNA-126 inhibits the proliferation of lung cancer cell line A549
Asian Pacific Journal of Tropical Medicine
;
(12): 239-242, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-951529
ABSTRACT
Objective:
To study the role of microRNA-126 in the development of lung cancer.Methods:
The biological function of microRNA-126 was detected using EdU assay and CCK-8 assay; the target gene of microRNA-126 was analyzed using real time RT-PCR and Western blot assay.Results:
In A549 cell line, overexpression of microRNA-126 inhibits the proliferation rate; VEGF is the target gene of microRNA-126; microRNA-126 exerts its function via regulating VEGF protein level.Conclusions:
microRNA-126 inhibits the proliferation in A549 cell line.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Asian Pacific Journal of Tropical Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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