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Hypericum caprifoliatum and Hypericum connatum affect human trophoblast-like cells differentiation and Ca
Asian Pacific Journal of Tropical Biomedicine ; (12): 367-373, 2014.
Artigo em Chinês | WPRIM | ID: wpr-951904
ABSTRACT

Objective:

To study the effect of crude methanol and n-hexane extracts of Hypericum connatum (H. connatum) and Hypericum caprifoliatum on trophoblast-like cells.

Methods:

BeWo and JEG-3 trophoblast-like cells were submitted to different extract concentrations (1, 5, 10 and 15 μg/mL) and evaluated in relation to cell viability and in vitro trophoblast differentiation and function. Cell viability was evaluated using WST-1 reagent. Differentiation was measured by luciferase production, hCG production/release, and mitogen-activated protein kinase signaling pathway activation. The function of the trophoblast-like cells was measured by

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2014 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Asian Pacific Journal of Tropical Biomedicine Ano de publicação: 2014 Tipo de documento: Artigo