Quantitative determination of multi-class bioactive constituents for quality control of Yiqi Jiangzhi Granules / 中草药·英文版
Chinese Herbal Medicines
;
(4): 324-331, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-953593
ABSTRACT
Objective:
To establish a reliable and sensitive method for evaluating quality of Yiqi Jiangzhi Granules (YQJZG).Methods:
Ultra performance liquid chromatography electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) was employed for simultaneous determination of eight marker components. Separation was performed on an AQUITY UPLC® HSS T3 column, the mobile phase consisted of acetonitrile as the organic phase and 0.1% (volume percentage) formic acid as the aqueous. Eight marker components, ginsenoside Rg1 (GRg1), ginsenoside Re (GRe), ginsenoside Rb1 (Gb1), typhaneoside (TEO), isorhamnetin-3-O-neohespeidoside (IN), hesperidin (HPD), aurantio-obtusin-6-O-β-D-glucoside (AG) and curcumin (CCM), were detected by multiple reaction monitoring (MRM) mode. The Chinese Pharmacopoeia (2020 edition) was regarded as the guidance document for this method validation.Results:
The method showed good linearity (R
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Herbal Medicines
Ano de publicação:
2022
Tipo de documento:
Artigo
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