Research progress on the effect mechanism of polysaccharides against pancreatic cancer / 中国药房
China Pharmacy
;
(12): 111-116, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-953729
ABSTRACT
Polysaccharide is a recognized immunomodulator that has been shown to have inhibitory effects on a variety of cancer cells and has the potential to be developed as an anti-cancer drug. Pancreatic cancer, one of the cancers with the highest mortality rate, is treated with long-term chemotherapeutic drugs and is prone to a variety of side effects such as immune deficiency, fatigue, and neurological lesions. The polysaccharide anti-pancreatic cancer research landscape both domestically and internationally is summarized in this publication. By regulating nuclear factor-κB, Hippo-Yes-associated protein, integrin and other signaling pathways, polysaccharide components play an anti-pancreatic cancer role by multi-target ways, such as inducing apoptosis and autophagy, inhibiting proliferation, migration and invasion of cancer cells, and regulating the cancer cell cycle.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2023
Tipo de documento:
Artigo
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