Progress on the role of TRIM8 protein in nervous system / 国际儿科学杂志

ABSTRACT

TRIM family proteins are considered to be E3 ubiquitin ligase, which involve in multiple biological processes.They participate in the genesis, development, proliferation and differentiation in the nervous system.TRIM8 is a member of TRIM family.TRIM8 plays divergent roles in many biological processes such as inflammation, tumor, cell proliferation.TRIM8 is involved in the pathological process of epilepsy, glioma, and stroke.This arttde reviews the role and mechanism of TRIM8 in nervous system diseases in order to provide new treatment ideas for the nervous system diseases.