Advances in diagnosis and treatment of multisystem inflammatory syndrome in children / 国际儿科学杂志

ABSTRACT

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection may lead to multisystem inflammatory syndrome in children(MIS-C). MIS-C mostly occurs in older children and adolescents who have laboratory or epidemiological evidence of SARS-CoV-2 infection.The clinical manifestations include persistent fever, hypotension, elevated inflammation markers, and symptoms of multiple organ involvement, which is similar to Kawasaki disease.Once the disease occurs, it can progress rapidly and worsen in a short time, and most children require intensive care admission.Although the overall prognosis is good, some patients have adverse results such as death.We should strengthen the monitoring and management of suspected children and improve the level of diagnosis and treatment of the disease.