Efficacy of the Troponin T Rapid Assay Kit in Early Diagnosis of Acute Myocardial Infarction
Korean Circulation Journal
;
: 1116-1121, 1995.
Artigo
em Coreano
| WPRIM
| ID: wpr-9547
ABSTRACT
BACKGROUND:
In the diagnosis of acute myocardial infarction, measurement of CK-MB is widely used as an enzyme test, but it needs special instruments, lacks specificity in the presence of concomitant skeletal muscle injuries, and has narrow diagnostic time window. Cardiac specific troponin T-a new marker for the diagnosis of myocardial injury-is now available. Besides the quantitative assay, rapid qualitative asay is also possible with the development of rapid assay Kit. We studied about the efficacy of the Troponin T rapid assay Kit in early doagnosis of actue myocardial infarction in the emergency room.METHODS:
Total Ck, Ck-MB, LDH and serum troponin T activities were determined when the patients arrived at the emergency room and at the same time Troponin T rapid assay kit test was done. Final diagnosis was made through the serial measurement of CK, CK-MB and LDH. Diagnostic efficacy of each rest was evaluated.RESULTS:
Overall diagnostic sensitivity and specificity of Troponin T rapid assay kit were 0.97 and 0.91. When evaluated only with the initial results, Troponin T rapid assay kit showed sensitivity 0.87, specificity 0.97, serum troponin T 0.75, 0.92, and Ck-Mb 0.81,0.95. In one patient who was finally diagnosed as a septic shock, Ck-MB was elevated but serum troponin T was not and Troponin T rapid assay kit test showed negative result.CONCLUSION:
Troponin T rapid assay kit test seems to show nearly the same sensitivity and specificity in diagnosis of acute myocardial infarction compared to CK-MB. This test can be done simply and easily in a short time. Thus, with the use of this test, morbidity, mortality and economic loss due to misdiagnosis and delay of diagnosis of myocardial infarction might be reduced.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Choque Séptico
/
Troponina
/
Mortalidade
/
Sensibilidade e Especificidade
/
Músculo Esquelético
/
Troponina T
/
Diagnóstico Precoce
/
Diagnóstico
/
Erros de Diagnóstico
/
Serviço Hospitalar de Emergência
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Pesquisa qualitativa
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Circulation Journal
Ano de publicação:
1995
Tipo de documento:
Artigo
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