Progress of the Nod-like receptor family pyrin domain-containing protein 12 in autoinflammatory diseases / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 1268-1272, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-954722
ABSTRACT
The Nod-like receptor family pyrin domain-containing protein 12(NLRP12), a newly discovered member of the Nod-like receptor family, is one of the important pattern recognition receptors.It recognizes a variety of pathogens, initiates downstream immune responses, and participates in the regulation of multiple inflammatory responses.NLRP12 is related to the occurrence and progression of inflammatory diseases.In this review, the structure and function of NLRP12 as well as NLRP12-associated autoinflammatory diseases were discussed, so as to provide new insights for the understanding, exploration and treatment of NLRP12-associated autoinflammatory diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Applied Clinical Pediatrics
Ano de publicação:
2022
Tipo de documento:
Artigo
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