Research progress of neutrophil extracellular traps in rheumatic diseases / 中华实用儿科临床杂志

ABSTRACT

Rheumatic diseases are inflammatory diseases characterized by severe immune dysregulation, which can affect tissues and joints.Neutrophils are the key factor contributing to immune disorders, and they play an important role in rheumatic diseases.Neutrophil extracellular traps (NETs) are network structures released by neutrophil granulocytes when stimulated.As a novel immune defense mechanism, NETs have attracted wide attention.In this paper, the formation, function and role of NETs in rheumatic diseases and other diseases were reviewed.