Research progress on the effects of fluoride on intestinal structure and defense function / 中华地方病学杂志

ABSTRACT

Fluorine is a non-metallic chemical element, which often exists in the form of fluoride in nature. Long-term excessive intake of fluoride will lead to chronic fluorosis. Fluoride is mainly absorbed through the digestive tract, so the intestinal tract is more vulnerable to fluoride damage. Excessive fluoride not only destroys intestinal structure and interferes with intestinal flora and micro-environment, but also induces intestinal toxicity through oxidative stress. This article reviews the effects of fluoride on intestinal structure and defense function, aiming to provide theoretical references and new ideas for the mechanism study of fluoride-induced intestinal damage.