High risk factors for endometrial polyps in 304 cases / 中国基层医药

ABSTRACT

Objective:To investigate the high risk factors for endometrial polyps (EP).Methods:The clinical data of 669 cases who underwent hysteroscopic examination due to abnormal vaginal bleeding and ultrasonic indications in Binzhou Medical University Hospital from October 2019 to September 2020 were retrospectively analyzed. According to postoperative pathological results, these patients were divided into an EP group ( n = 304) and a non-EP group ( n = 365). The clinical data of these patients were subjected to univariate and multivariate analysis using SPSS 22.0 software. Results:Univariate analysis showed that age (median age 45 years in the EP group and 47 years in the non-EP group), number of pregnancies (median number of pregnancies 2 in the EP group and 3 in the non-EP group), number of births (median number of births 1 in the EP group and 2 in the non-EP group), menopause [49 cases (16.12%) in the EP group and 83 cases (22.74%) in the non-EP group], chronic endometritis [111 cases (36.51%) in the EP group and 174 patients (47.67%) in the non-EP group], cervical polyps [58 cases (19.08%) in the EP group and 46 cases (12.06%) in the non-EP group], hypertension [48 cases (15.79%) in the EP group and 88 cases (24.11%) in the non-EP group], diabetes mellitus [14 cases (4.61%) in the EP group and 31 cases (8.49%) in the non-EP group] were the risk factors of EP ( Z =-3.71, -4.30, -2.50, χ2 = 4.59, 8.44, 0.02, 0.01, 0.04, all P < 0.05). Multivariate analysis showed that age, number of pregnancies, chronic endometritis and cervical polyps had significant effects on the incidence of EP ( OR = 0.97, 95% CI 0.95-0.99, OR = 0.80, 95% CI 0.72-0.90, OR = 0.53, 95% CI 0.38-0.74, OR = 1.73, 95% CI 1.10-2.72, all P < 0.05). Conclusion:Age, number of pregnancies, chronic endometritis and cervical polyps are all risk factors for the development of endometrial polyps.