Evaluation of left ventricular energy loss by vector flow mapping in patients with systemic lupus erythematosus / 中华超声影像学杂志

ABSTRACT

Objective:To analyze the changes of energy loss(EL) in systemic lupus erythematosus(SLE) patients and the relationship between EL and cardiac function by vector flow mapping(VFM).Methods:The intraventricular hemodynamics of 60 females with SLE(SLE group) and 61 healthy female controls(control group) who attended the First Affiliated Hospital of Nanjing Medical University from August 2015 to August 2019 were compared, and cardiac function changes were evaluated using VFM. The EL at each segment of the left ventricular chamber (total, basal, middle, and apical segments) during each period of the cardiac cycle (isovolumic contraction, rapid ejection, rapid filling, reduced filling, atrial contraction) were analyzed. Relationship between EL and clinical and echocardiographic parameters was analyzed.Results:In SLE group, EL decreased from basal to middle to apical segments, with significant difference (all P<0.01). Compared with the control group, EL in early, middle, late diastole and rapid ejection period in SLE group was significantly increased (all P<0.01). During the rapid filling period, the EL was positively correlated with septal E′ ( r=0.784, P<0.001), and during the atrial contraction period EL was positively correlated with septal E/e′ ( r=0.812, P<0.001) and A ( r=0.715, P<0.001). During isovolumic contraction period, EL was positively correlated with interval E/e′, peak A ( r=0.461, 0.672; all P<0.001). Conclusions:VFM of patients with SLE can comprehensively, rapidly, and efficiently evaluate changes of myocardial mechanics and intracardiac hemodynamics, and provide quantitative analysis of complex intracardiac blood flow.