Intraoperative radiotherapy in borderline resectable pancreatic carcinoma / 中华肝胆外科杂志

ABSTRACT

The adjacency or invasion to great vessels such as superior mesenteric artery/vein and celiac axis increase the difficulties to achieve R 0 resection and evoked high local recurrence for patients with borderline resectable pancreatic cancer. Intraoperative radiation therapy refers to a single high-dose irradiation during the surgery, which achieved the purpose of precise target treatment and protected normal tissues. In borderline resectable pancreatic cancer, preoperative radiotherapy and chemotherapy combined with surgery and intraoperative radiotherapy has a better effect, and compared with surgery alone, the addition of intraoperative radiotherapy does not increase the risk of serious postoperative complications. Here, we summarized the application of intraoperative radiation therapy in borderline resectable pancreatic carcinoma.