Advance in metabolomics based research of polycystic ovary syndrome / 中华内分泌代谢杂志

ABSTRACT

The main characteristics of polycystic ovary syndrome (PCOS) are hyperandrogen, ovulation disorder, insulin resistance and obesity. However, its pathogenesis is not completely understood. Therefore, it is very important to study the metabolic pathways that may be related to PCOS and find its metabolic markers. The application of metabolomics provides a new direction for studying the pathogenesis of PCOS. It is a very valuable and developing technology that can discover new metabolites and explore potential biomarkers for endocrine and metabolic diseases. In addition, metabolomics technology can also improve the diagnosis and treatment of PCOS. This article aims to summarize the recent applications and research progress of metabolomics in PCOS, elaborating on metabolites and metabolic pathways.