Importance of the standardized clinical application and evaluation of renal injury markers / 中华检验医学杂志

ABSTRACT

Chronic Kidney Disease (CKD) has become one of the main diseases severally threatening human health, which has aroused global attention. Acute Kidney Injury (AKI) is the main cause of CKD. Early diagnosis of AKI is the most effective way to prevent CKD. More and more new biomarkers of renal injury will be found through genomics, proteomics, and metabolomics methodologies. The clinical application of a single marker in the real world will be subject to certain restrictions because of the etiological diversity and personal differences. Kidney damage monitoring models will be established by artificial intelligence method. However, standardizing the evaluation of its clinical application value is essential to screen out truly valuable kidney injury biomarkers or monitoring models, to promote the clinical application of kidney injury markers, and to effectively reduce the incidence of CKD.