Progress of pyroptosis in gynecological diseases / 肿瘤研究与临床

ABSTRACT

Pyroptosis is a fairly new type of cell death that is frequently mediated by inflammasomes and is strongly related to Gasdermin protein family and cysteinyl aspartate specific proteinase (caspase). The importance of pyroptosis-related molecules in the occurrence and progression of gynecological diseases cannot be overstated. This article reviews the related mechanism of cell pyroptosis, and the relationship between pyroptosis and benign and malignant gynecological diseases, so as to provide references for the research of the diagnosis and treatment of gynecological diseases, as well as the development of targeted drugs.