Effects of Morroniside on Rats Neurons in Focal Cerebral Ischemia/Reperfusion Injury / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
; (12): 27-28, 2010.
Article
em Zh
| WPRIM
| ID: wpr-959190
Biblioteca responsável:
WPRO
ABSTRACT
@#ObjectiveTo investigate the effects of morroniside on super oxide dismutase (SOD) and neurons in rats cortex with focal cerebral ischemia/reperfusion. MethodsThe animal model was induced by middle cerebral artery occlusion with suture embolus, cerebral ischemia 30 min and reperfusion 3 d or 7 d. Vitamin E for the positive control. The content of SOD was detected with spectrophotometry and the nerve cells was observed with immunohistochemistry. ResultsCompared with model group, morroniside (270 mg/kg)increased the activity of SOD and the number of neurons (30 mg/kg, 90 mg/kg, 270 mg/kg) significantly. ConclusionMorroniside may have neuroprotective effect and increasing the activity of SOD in rats cortex.
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WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Rehabilitation Theory and Practice
Ano de publicação:
2010
Tipo de documento:
Article