A new method of treatment of experimental uremia in dogs

ABSTRACT

The study described the use of human placenta as a dialyzing medium. This is a preliminary reportThe subject was a dog legated to produced uremia. A freshly delivered placenta was obtained. The two arteries and the vein of the umbilical cord were cannulated separately using glass cannules. The femoral vessels of the dog were exposed and cannulated on both sides. The cannulated vessels of the dog and the placent were connected to establish a closed circulation, such that the dogs blood flowed from the femoral arteries to the umbilical arteries through the placenta to the umbilical vein, then back to the femoral vein of the dog and its general circulationThe establishment of circulation through the placenta was satisfactory. The NPN and creatinine levels were determined and recorded.(Author)