Efficacy of calcitonin gene-related peptide antagonists in the treatment of acute migraine: A systematic review and meta-analysis
Acta Medica Philippina
;
: 44-51, 2019.
Artigo
| WPRIM
| ID: wpr-959763
ABSTRACT
Objective:
This study determined the efficacy of calcitonin gene-related peptide (CGRP) antagonists in the treatment of acute migraine.Methods:
Seven randomized, controlled trials were included. Outcome measures used were pain freedom and pain relief two hours after treatment.Results:
The difference in pain freedom 2 hours post-dose significantly favored gepants 140/150 mg (OR=2.39, 95% CI=1.93-2.96, PConclusion:
With regard to pain freedom and pain relief two hours post-dose, CGRP antagonists are more efficacious than placebo in the treatment of acute migraine but there is insufficient evidence to demonstrate superior efficacy of CGRP antagonists over triptans.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dor
/
Triptaminas
/
Peptídeo Relacionado com Gene de Calcitonina
/
Transtornos de Enxaqueca
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Limite:
Humanos
Revista:
Acta Medica Philippina
Ano de publicação:
2019
Tipo de documento:
Artigo
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