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Recurrent hydatidiform mole with NLRP7 mutation: The first confirmed case in the Philippines / Philippine Journal of Obstetrics and Gynecology
Philippine Journal of Obstetrics and Gynecology ; : 27-32, 2017.
Artigo | WPRIM | ID: wpr-960575
ABSTRACT
High gravidity hydatidiform mole (HM) without normal pregnancy is very rare. The challenge of managing such cases will dwell on the concern of having normal conception versus having another molar gestation and its neoplastic sequelae.Presented in this paper is a case of a 32-year-old, gravida 5 para 0 (0040) who was admitted for the management of her fifth molar pregnancy. She underwent suction curettage and administration of methotrexate chemoprophylaxis. Genetic testing was done, which revealed a homozygous mutation in NLRP7, the gene implicated in recurrent molar gestations. This paper discusses the proper approach to determine the cause of recurrent molar pregnancies, as well as the management and prognosis of such cases.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Curetagem a Vácuo / Mola Hidatiforme / Testes Genéticos / Metotrexato / Quimioprevenção / Número de Gestações / Homozigoto / Dente Molar / Mutação Limite: Adulto / Feminino / Humanos Revista: Philippine Journal of Obstetrics and Gynecology Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Curetagem a Vácuo / Mola Hidatiforme / Testes Genéticos / Metotrexato / Quimioprevenção / Número de Gestações / Homozigoto / Dente Molar / Mutação Limite: Adulto / Feminino / Humanos Revista: Philippine Journal of Obstetrics and Gynecology Ano de publicação: 2017 Tipo de documento: Artigo