Correlation of cranial CT scan findings with positive & negative symptoms in chronic Schizophrenics

ABSTRACT

OBJECTIVE@#This study was conducted to determine whether there was a correlation between structural brain abnormalities among the different symptom subsets of schizophrenia. @*METHODOLOGY@#Male chronic schizophrenics from Bocaue, Bulacan were screened using the Positive & Negative Symptom Scale (PANSS) and were then subjected to cranial CT scan. Measurements of the lateral ventricles, third ventricle and interhemispheric fissure were obtained and compared with measurements of normal controls. Values were also compared between positive and negative subsets. @*RESULTS@#Using the Kruskall-Wallis test for 2 groups with 95% confidence interval, it was shown that there was no statistical difference in any of the measurements between control and schizophrenic patients, as well as between the positive and negative symptom subset.@*CONCLUSION@#This study did not support the findings of the previously cited reports. Measurements of the schizophrenic group were statistically negligible when compared with the normal and were also insignificant between symptom subsets.