Risk factors for recurrent papillary thyroid carcinoma
Philippine Journal of Otolaryngology Head and Neck Surgery
;
: 25-29, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-961023
ABSTRACT
@#<p style="text-align justify;"><strong>OBJECTIVE:
</strong> To identify risk factors associated with disease recurrence among Filipinos with papillary thyroid carcinoma (PTC).<br /><strong>METHODS:
</strong><br /><strong>Design:
</strong> Retrospective Cohort Study<br /><strong>Setting:
</strong> Tertiary National University Hospital<br /><strong>Participants:
</strong> 76 patients diagnosed with papillary thyroid carcinoma, classified as low and low-to-intermediate risk (2015 ATA classification) that underwent total thyroidectomy with or without neck dissection from 2010-2014 and were followed up from 10 months to 5 years. Log rank and Cox regression analyses were used to determine significant risk factors for recurrence.<br /><strong>RESULTS:
</strong> 29 (38.15%) had recurrence. On univariate analysis, age, tumor size, multifocality, extrathyroidal extension, presence of lateral neck nodes and RAI therapy were statistically associated with recurrence. However, on multivariate analysis, no clinicopathologic factor was statistically associated with recurrence.<br /><strong>CONCLUSION:
</strong> Age of >45 years, female sex, tumor size of >2 cm, multifocality, presence of microscopic extrathyroidal extension and lymph node metastasis might contribute to the recurrence of papillary thyroid cancer while post-operative radioactive ablation may have some protective effect. However, this study suggests that other factors must be included in the model to better understand the relationship between these factors and recurrence.</p>
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WPRIM (Pacífico Ocidental)
Assunto principal:
Esvaziamento Cervical
/
Tireoidectomia
/
Fator IX
/
Neoplasias da Glândula Tireoide
/
Análise de Regressão
/
Câncer Papilífero da Tireoide
/
Linfonodos
/
Metástase Linfática
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Philippine Journal of Otolaryngology Head and Neck Surgery
Ano de publicação:
2017
Tipo de documento:
Artigo
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