Maxillary sinus squamous cell carcinoma in a tertiary hospital in the Philippines

ABSTRACT

@#<p><strong>Objective:</strong> To establish preliminary demographic and clinicopathologic data on Maxillary Sinus Squamous Cell Carcinoma (SCC) in the Philippine General Hospital</p><p><strong>Methods:</strong>       </p><p><strong>Design:</strong>           Retrospective Case Series</p><p><strong>Setting:</strong>           Tertiary National University Hospital</p><p><strong>Participants:</strong> Socio-demographic and clinical data from records of 22 patients admitted at the Department of Otorhinolaryngology of the Philippine General Hospital from 2013-2016 and histopathologically confirmed to have Maxillary Sinus SCC, were collected and described using means and proportions.</p><p><strong>Results:</strong> There were 15 males and 7 females with a mean age of 50-years-old (range 24 to 77-years-old). Maxillary mass/swelling was the most common chief complaint.  The mean gap between initial symptoms and consult was 6.77 months.  Initial biopsies were obtained from the maxillary sinus in 16 patients, with 1 patient noted to have undergone malignant transformation from a prior intranasal squamous papilloma.  Staging was advanced (Stage IVA in 16, IVB in 4, and III in 2), with no patients with Stage I or II disease.  Sixteen (16) patients underwent surgery and radiotherapy, while 6 patients received radiotherapy (RT) with or without chemotherapy.  Regional and distant metastases were uncommon.</p><p><strong>Conclusion:</strong> In this series, maxillary sinus SCC occurs more in males, with a maxillary mass as the most common chief complaint.  Delay in treatment is common, with a mean gap of 6 months between initial symptoms and consult.  Neck node metastasis is uncommon, and most patients undergo surgery with radiotherapy as treatment.</p><p> </p><p><strong>Keywords</strong> maxillary sinus cancer; paranasal sinus cancer; squamous cell carcinoma</p>