Sulfathiazole in certain acute infections: preliminary report

ABSTRACT

1. Twenty-seven cases of various forms of acute infection were treated with sulfathiazole2. The pneumonias, erysipelas, acute tracheo-bronchitis, acute cellulitis of the leg, puerperal fever, and a case of acute circumscribed inflammation of the auditory canal were favorably influenced by the drug. In acute gonorrhea, acute pleurisies, and in one case of facial cellulitis with abscess, sulfathiazole was a failure.3. The side-effects noted in my series were convulsion cyanosis in 3 cases, drug fever and diarrhea in another, and morbilliform rashes in 3. All of these patients were of ages ranging from 1.5 months to 5 years. None of my adult patients developed any toxic manifestations4. Sulfathiazole seems to be a useful therapeutic agent in the treatment of the pneumonias, acute tracheo-bronchitis, acute cellulitis, erysipelas, puerperal fever, and in beginning acute circumscribed inflammation of the auditory tube.(Summary and Conclusion)