Renal biopsy studies in the nephrotic syndrome among Filipino adults

ABSTRACT

This is a report of five cases with the nephrotic syndrome. All of these patients were adults whose ages ranged from 17 to 38. The underlying etiological mechanisms responsible for the development of the syndrome remained undisclosed in most of the cases in spite of complete clinical and laboratory work-up. Percutaneous renal biopsy studies were performed on all cases. Biopsy findings revealed changes consistent with Ellis Type II glomerulonephritis in 2 of the cases, whereas no glomerular abnormalities could be seen in 3 of the casesThe limitations of light microscopy to demonstrate early alterations within the glomeruli of subjects suffering from the nephrotic syndrome were discussed. (Summary)