Role of non-coding RNAs in vascular smooth muscle cell calcification / 生理学报
Acta Physiologica Sinica
;
(6): 885-893, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-970084
ABSTRACT
Vascular calcification, the deposition of calcium in the arterial wall, is often linked to increased stiffness of the vascular wall. Vascular calcification is one of the important factors for high morbidity and mortality of cardiovascular and cerebrovascular diseases, as well as an important biomarker in atherosclerotic cardiovascular events, stroke and peripheral vascular diseases. The mechanism of vascular calcification has not been fully elucidated. Recently, non-coding RNAs have been found to play an important role in the process of vascular calcification. In this paper, the main types of non-coding RNAs and their roles involved in vascular smooth muscle cell calcification are reviewed, including the changes of osteoblast-related proteins, calcification signaling pathways and intracellular Ca2+.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Miócitos de Músculo Liso
/
Calcificação Vascular
/
Músculo Liso Vascular
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Physiologica Sinica
Ano de publicação:
2022
Tipo de documento:
Artigo
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