Research progress of the regulatory role of autophagy in metabolic liver diseases / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 105-108, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-970960
ABSTRACT
Autophagy is one of several hepatic metabolic processes in which starved cells are supplied with glucose, free fatty acids, and amino acids to produce energy and synthesize new macromolecules. Moreover, it regulates the quantity and quality of mitochondria and other organelles. As the liver is a vital metabolic organ, specific forms of autophagy are necessary for maintaining liver homeostasis. Protein, fat, and sugar are the three primary nutrients that can be altered by different metabolic liver diseases. Drugs that have an effect on autophagy can either promote or inhibit autophagy, and as a result, it can either increase or inhibit the three major nutritional metabolisms that are affected by liver disease. Thus, this opens up a novel therapeutic option for liver disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Autofagia
/
Fígado
/
Hepatopatias
/
Doenças Metabólicas
/
Mitocôndrias
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2023
Tipo de documento:
Artigo
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