Clinicopathological characteristics and treatment outcomes of 38 cases of primary thyroid lymphoma: a multicenter study
Annals of Surgical Treatment and Research
;
: 295-299, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-9719
ABSTRACT
PURPOSE:
Primary thyroid lymphoma (PTL) is a rare disease and it has been investigated in a limited number of studies. The present multicenter study evaluated the clinical features and treatment outcomes of PTL.METHODS:
The medical records of patients diagnosed with PTL between 2000 and 2013 in three centers were retrospectively reviewed.RESULTS:
The study included 11 men and 27 women with a median age of 63.3 years (range, 42-83 years). The median follow-up was 56.0 months (range, 3-156 months). Of the 38 patients included, 16 had mucosa-associated lymphoid tissue (MALT) lymphoma, six had mixed MALT and diffuse large B-cell lymphoma (DLBCL), and 16 had DLBCL. Thirty-five patients (92.1%) had early stage (stage I/II) disease. Of the 16 MALT lymphoma patients, 14 were treated by surgery, and radiotherapy (RT) or chemotherapy was combined in five patients. Two patients received RT or chemotherapy alone. Of the six mixed MALT and DLBCL patients, three underwent surgery with chemotherapy and three underwent chemotherapy alone, RT alone, or surgery with RT. All of the 16 DLBCL patients received chemotherapy, and surgery and RT was combined in 4 and 1 patients, respectively. The 5-year survival was 100% for MALT lymphoma (7 of 7) and mixed MALT and DLBCL patients (5 of 5) and 87.5% for DLBCL patients (7 of 8).CONCLUSION:
Early stage PTL has an excellent prognosis when managed by single or combined treatment modalities. Clinicians should consider PTL in patients with underlying Hashimoto's thyroiditis presenting with an enlarging thyroid mass.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Radioterapia
/
Glândula Tireoide
/
Tireoidite
/
Prontuários Médicos
/
Estudos Retrospectivos
/
Seguimentos
/
Linfoma de Células B
/
Linfoma de Zona Marginal Tipo Células B
/
Doenças Raras
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Annals of Surgical Treatment and Research
Ano de publicação:
2015
Tipo de documento:
Artigo
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