Relativity between Changes of 1H-MRS in Hippocampus and Prefrontal Lobe and the Syndrome Differentiation of Major Depression / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 960-962, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-972099
ABSTRACT
@#Objective To explore the relativity between the changes of 1H magnetic resonance spectroscopy(1H-MRS) in hippocampus and prefrontal lobe and syndrome differentiation of major depression.Methods Sixty patients with major depression(MD) were divided into Group A(phlegm-heat syndrome),Group B(blood stasis syndrome),Group C(deficient fire syndrome) and Group D(cold-dampness syndrome),and other 20 normal controls were selected.The neurochemical abnormalities including the ratios of N-acetylaspartate(NAA)/choline(Cho),NAA/creatine(Cr) and Cho/Cr were measured with three-dimension 1H proton magnetic resonance spectroscopy(3D1H-MRS).Results The ratios of Cho/Cr in white matter of the prefrontal lobe were significant higher in MD patients than that in normal controls(P<0.05);the ratios of NAA/Cr in hippocampus were significant higher in MD patients than that in normal controls(P<0.05).Conclusion There might be the relativity between the neurochemical abnormalities in hippocampus and prefrontal lobe and traditional Chinese medicine syndrome differentiation of major depression.
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Rehabilitation Theory and Practice
Ano de publicação:
2008
Tipo de documento:
Artigo
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