Analysis of pathogenesis of bile's tri-pa tumor or gallstones and the mechanism of some traditional drug action / Монголын Анагаах Ухаан

ABSTRACT

Background@#Some scholars believe that the study ancient medical works to gain insight into their scientific concepts and correctly understand the profound techniques of doctors are very important to development of traditional medicine in the 21st century. In “The WHO Traditional Medicine Strategy 2014-2023”, strengthen the study of traditional medical books is mentioned. According to epidemiological surveys, gallstones are a common disease worldwide. In the “Oral Instruction Tantra”, pathogenesis and treatment of gallstones mentioned and further refined in the Interpretation books. Although in modern times, doctors have published many papers and books on traditional medical treatment of gallstones and their pathogenesis based on the contents of ancient books and their own clinical experience, but in-depth analysis of the literature information and explanations have not been mentioned in detail.@*Goal @#According to the traditional medical theory to analyze the pathogenesis of bile’s Tri-pa tumor or gallstones and the mechanism of some drug action.@*Materials and methods@#In our study, we used the book named “Oral Instruction Tantra” as main reference material and for research methods, we used the checklist method to list relevant information about the pathogenesis of gallstones and Nemert Yvuunii Uns-10 traditional drug from the literature, so as to provide preconditions for further analysis. The pathogenesis of gallstones and the action mechanism of Nemert Yvuunii Uns-10 were analyzed by theoretical analysis methods and the analysis-synthesis method was used to summarize the analysis results. </br>The study was carried out in accordance with “Academic Staff Code of Ethics” in the appendix of Ministerial Decree No. 454 in 2007.12.03 by Ministry of Education, Culture and Science,Mongolia. @*Results @#Affected by constitution, unaccustomed diet, inharmonious diet and naturally difficult to digest food, stomach fire reduced leads to food can not be corroded by decomposing phlegm, can not be melting by digestive bile and can not be separated by fire-accompanying wind. This causes food waste enter the nutritional essence which is transported to the liver. The pathological blood is produced when color-producing bile in the liver processes nutritional essence and eventually, bile’s Tri-pa tumor or gallstones are caused by the accumulation of bile deposits from the pathological blood under the influence of wind. </br>We using Mongolian medicine theory to analyze the mechanism of action of Nemert Yvuunii Uns-10 in treating gallstones. In the prescription, Manufactured Monetaria moneta (Linnaeus), Calcitum and Boar dung are main ingredients, Have a crushing Tri-pa tumor or gallstones effect. The function of the Aucklandia lappa Decne supplement the efficacy of the main ingredients. Trogopterori Faeces, Lagotis Integrifolia and Carthamus tinctorius L. treat pathologic blood in the liver. Gentiana Barbata and Herpetospermum caudigerum Wall hava a reducing bile heat effect. Punica granatum L. has the effect of increasing stomach fire and promoting digestive function. Terminalia chebula Retz. homogenize the three humorus.@*Conclusions@#Reduced stomach fire leads to the production of pathological blood in the liver and eventually accumulation of deposits in bile is the cause of bile’s Tri-pa tumor or gallstones. The mechanism of action of Nemert Yvuunii Uns-10 traditional drug for treat bile’s Tri-pa tumor or gallstones is by breaking stones, treating pathological blood, reducing bile heat, increasing stomach fire to promote digestion and homogenizing the three elements