Multifocal motor neuropathy with Anti-GM1 antibody: A Filipino case report
Journal of Medicine University of Santo Tomas
;
(2): 541-545, 2020.
Artigo
em Inglês
| WPRIM
| ID: wpr-974245
ABSTRACT
@#As far as we are aware of, we report the fi rst documented case of a 51-year-old Filipino female with multifocal motor neuropathy who presented with asymmetric weakness, unusually in the lower extremity, and confi rmed with anti-GM1 antibody. The treatment of intravenous immunoglobulin with a total dose of 2 g/kg was initiated and repeated every two months with noticeable improvement based on electromyography and nerve conduction studies. Apart from the unreported Filipino case of multifocal motor neuropathy substantiated by features in clinical, electrophysiologic, antibody testing and response to immunotherapy, the unique occurrence in a female and involving the lower extremity in this rare disorder deserve this present documentation. Multifocal motor neuropathy is seen more in males with a ratio of 2.71. It is described as a pure motor disease without sensory defi cits and predominantly affects the upper extremities. The diagnosis for the disorder is supported by determination of ganglioside GM1 antibodies.
Buscar no Google
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polineuropatias
/
Doenças do Sistema Imunitário
Idioma:
Inglês
Revista:
Journal of Medicine University of Santo Tomas
Ano de publicação:
2020
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS