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Effect of Paroxetine on Post-stroke Depression / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice ; (12): 597-598, 2006.
Artigo em Chinês | WPRIM | ID: wpr-974769
ABSTRACT
@#ObjectiveTo observe the efficacy and side effects of paroxetine and amitriptyline in the treatment of post-stroke depression (PSD).Methods82 PSD patients were randomly divided into the paroxetine group (n=42) and amitriptyline group (n=40). Before the treatment and at the ends of 2nd, 4th and 8th week after the treatment, all patients in two groups were assessed with Hamilton Depression Scale (HAMD) and TESS.ResultsAfter treatment, HAMD scores of patients of two groups were decreased significantly (P<0.01), but no difference was found between two groups. The side effects of the paroxetine group were obviously fewer and milder than that of amitriptyline group (P<0.01).ConclusionParoxetine is an effective and safe drug in the treatment of PSD.

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Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Rehabilitation Theory and Practice Ano de publicação: 2006 Tipo de documento: Artigo

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Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Rehabilitation Theory and Practice Ano de publicação: 2006 Tipo de documento: Artigo