Effects of Srog dzin-5 prescription on pathogenesis model of acute stress and animal models of depressive disorders / Монголын эм зүй, эм судлал

ABSTRACT

Abstract@#There is a growing need for a systematic study of the use of medicines prepared from herbal, animal, and mineral raw materials in traditional Mongolian medicine to a new level. Based on traditional medicine technology and use, the study identified the most suitable modern medicinal ingredients for the human body, namely a medicine that can be used for depression in the ancient scripture, “Ngo mtshar dga’ ston gter mdzod” by Gelen Choijamts and further practical application is imperative. @*Purpose@#To study the effects of Srog dzin-5 prescription on pathogenesis model of acute stress and animal models of depressive disor- ders. @*Conclusion@#</br>1. In the pathogenesis model of acute stress disorder caused by restricted mobility, Srog dzin-5 prescription prevents stress-induced thymic involution and enlargement of adrenal glands. </br>2. In the pathogenesis model of ethanol-induced depression, Srog dzin-5 prescription increased physical activity, reduced despair, and prevented anxiety according to behavioral assessment.