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Clinical Observation on Effect of Nicorandil in Angina Pectoris
Korean Circulation Journal ; : 519-525, 1987.
Artigo em Coreano | WPRIM | ID: wpr-97562
ABSTRACT
We evaluated the clinical effects of Nicorandil in 27 patients (17 male and 10 female) with ischemic heart disease (17 patients of stable effort angina, 3 patients of unstable effort angina, 6 patients of spontaneous angina, 1 patient of variant angina) in terms of the effect on the anginal pain, electrocardiographic changes and side effects. The results obtained were as follows; 1. The pulse rate was not changed by the drug administration and blood pressure were decreased slightly by Nicorandil in a daily dose of 15 mg divided into 3 dose, but these decrease were not significant in statistical meaning. 2. Improvement in EKG changes was observed in 9 patients (69%) among the 13 patients who showed abnormal EKG initially. 3. Anti-anginal effect of nicorandil were excellent in 14 patients, good in 8 patients, fair in 3 patients and so the rate of global improvement was 82%. 4. Nicorandil had side effects in 7 patients, headache (4 patients), palpitation, ocular pain, edema, but these were transitory and tolerable except of one case who could not be continued because of severe headache.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pressão Sanguínea / Isquemia Miocárdica / Nicorandil / Edema / Eletrocardiografia / Cefaleia / Frequência Cardíaca / Angina Pectoris Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Circulation Journal Ano de publicação: 1987 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pressão Sanguínea / Isquemia Miocárdica / Nicorandil / Edema / Eletrocardiografia / Cefaleia / Frequência Cardíaca / Angina Pectoris Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Circulation Journal Ano de publicação: 1987 Tipo de documento: Artigo