Research progress on the development of human neutrophil elastase inhibitors / 药学学报
Acta Pharmaceutica Sinica
;
(12): 909-918, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-978760
ABSTRACT
Human neutrophil elastase (hNE) is a serine proteolytic enzyme mainly distributed in neutrophils. When the balance between anti-hNE protein and hNE is broken, excessive release of hNE can cause the occurrence of various diseases. Therefore, inhibition of hNE is a promising therapeutic strategy. In this paper, the structure, action mechanism, physiological function of hNE and the development of hNE inhibitors were briefly summarized, in order to provide information for the related research.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2023
Tipo de documento:
Artigo
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