A preliminary study on the safety, efficacy and acceptability of the community preparation of Siling Labuyo (Capsicum frutescens) Liniment in the management of Knee Osteoarthritis in a six-week, active-controlled community-based clinical trial
Acta Medica Philippina
;
: 327-334, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-979026
ABSTRACT
Objective@#The study determined the safety, efficacy and acceptability of a Philippine community preparation of Siling Labuyo liniment in the management of knee osteoarthritis.@*Methods@#A 6-week randomized, double-blind, active-controlled clinical trial was conducted in three municipalities of Cavite from 2017-2018. The municipalities were randomly assigned to either the control or experimental group, using a commercially available Diclofenac 1% gel as the control agent. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Pain Visual Analogue Scale (VAS) were used to measure the outcomes.@*Results@#Forty-seven participants completed the study. Statistically significant improvement (p<0.05) in pain relief, reduction of symptoms and increase in knee functionality was reported by participants in both the experimental and control groups. Across the dimensions measured, at least 30% improvement in scores was reported by the experimental group, and at least 40% by the control group. The difference was statistically not significant (p>0.05). Itching (13%), burning sensation (11%) and reddening of the skin (15%) were experienced in both the experimental and the active control groups.@*Conclusion@#Use of the liniment led to a modest therapeutic effect and was well-tolerated by the participants.
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dor
/
Diclofenaco
/
Osteoartrite do Joelho
Idioma:
Inglês
Revista:
Acta Medica Philippina
Ano de publicação:
2018
Tipo de documento:
Artigo
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