Advances in Medical Treatment of Primary Aldosteronism / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
;
(4): 49-56, 2023.
Artigo
em Inglês
| WPRIM
| ID: wpr-981585
ABSTRACT
Primary aldosteronism (PA) is the most common form of secondary hypertension, with its main manifestations including hypertension and hypokalemia. Early identification of PA is extremely important as PA patients can easily develop cardiovascular complications such as atrial fibrillation, stroke, and myocardial infarction. The past decade has witnessed the rapid advances in the genetics of PA, which has shed new light on PA treatment. While surgery is the first choice for unilateral diseases, bilateral lesions can be treated with mineralocorticoid receptor antagonists (MRAs). The next-generation non-steroidal MRAs are under investigations. New medications including calcium channel blockers, macrophage antibiotics, and aldosterone synthase inhibitors have provided a new perspective for the medical treatment of PA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Adrenalectomia
/
Aldosterona
/
Antagonistas de Receptores de Mineralocorticoides
/
Hiperaldosteronismo
/
Hipertensão
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Medical Sciences Journal
Ano de publicação:
2023
Tipo de documento:
Artigo
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