Progress of research on the role of Atoh1 gene in the regeneration of mammalian auditory hair cells / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 614-617, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-981799
ABSTRACT
Atoh1 gene encodes a helix-loop-helix transcription factor which is involved in the generation and differentiation of mammalian auditory hair cells and supporting cells, and regulation of the proliferation of cochlear cells, therefore plays an important role in the pathogenesis and recovery of sensorineural deafness. This study reviews the progress of the Atoh1 gene in hair cell regeneration, with the aim of providing a reference for the study of hair cell regeneration gene therapy for sensorineural deafness.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Regeneração
/
Fatores de Transcrição
/
Diferenciação Celular
/
Surdez
/
Fatores de Transcrição Hélice-Alça-Hélice Básicos
/
Células Ciliadas Auditivas
/
Perda Auditiva Neurossensorial
/
Mamíferos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2023
Tipo de documento:
Artigo
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