Research updates of C1q/TNF related proteins (CTRPs) in inflammation-related diseases / 细胞与分子免疫学杂志
Chinese Journal of Cellular and Molecular Immunology
;
(12): 649-655, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-981912
ABSTRACT
Inflammation underlies a wide variety of physiological and pathological processes, and plays a pivotal role in controlling pathogen infection. C1q/tumor necrosis factor (TNF) related proteins (CTRPs), a newly discovered adipokine family with conservative structure and wide distribution, has attracted increasing attention. The CTRP family consists of more than 15 members which fall into the characteristic C1q domain. Increasing studies have demonstrated that CTRPs are involved in the onset and development of inflammation and metabolism as well as related diseases, including myocardial infarction, sepsis and tumors. Here, we first clarified the characteristic domains of CTRPs, and then elucidated their roles in inflammatory-related diseases. Taken together, the information presented here provides new perspectives for therapeutic strategies to improve inflammatory and metabolic abnormalities.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complemento C1q
/
Fator de Necrose Tumoral alfa
/
Inflamação
/
Infarto do Miocárdio
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Cellular and Molecular Immunology
Ano de publicação:
2023
Tipo de documento:
Artigo
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