Research progress on the preparation and application of flavonoid nanocrystals / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 338-348, 2023.
Artigo
em Inglês
| WPRIM
| ID: wpr-982051
ABSTRACT
Flavonoids have been reported to possess significant pharmacological activities,such as antioxidant, anti-inflammatory and anticancer effects. However, the low solubility and low bioavailability limits their clinical application. Nanocrystal technology can solve the delivery problems of flavonoids by reducing particle size, increasing the solubility of insoluble drugs and improving their bioavailability. This article summaries nanosuspension preparation methods and the stabilizers for flavonoid nanocrystals, and reviews the drug delivery routes including oral, Injection and transdermal of flavonoid nanocrystals, to provide information for further research on nanocrystal delivery system of flavonoids.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tamanho da Partícula
/
Flavonoides
/
Preparações Farmacêuticas
/
Disponibilidade Biológica
/
Nanopartículas
/
Anti-Inflamatórios
Idioma:
Inglês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2023
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS