Lethal anaphylactic shock model induced by human mixed serum in guinea pigs / 法医学杂志
Journal of Forensic Medicine
;
(6): 169-170, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-983099
ABSTRACT
OBJECTIVE@#To establish an anaphylactic shock model induced by human mixed serum in guinea pigs.@*METHODS@#Eighteen guinea pigs were divided into two groups sensitized and control, The sensitized group were immunized intracutaneously with human mixed serum and then induced by endocardiac injection after 3 weeks.@*RESULTS@#Symptoms of anaphylactic shock appeared in the sensitized group. The level of serum IgE were increased in the sensitized group significantly.@*CONCLUSIONS@#An animal model of anaphylactic shock wer established successfully. It provide a tool for both forensic study and anaphylactic shock therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Imunoglobulina G
/
Radioimunoensaio
/
Alérgenos
/
Distribuição Aleatória
/
Morte Súbita
/
Soro
/
Modelos Animais de Doenças
/
Medicina Legal
/
Cobaias
/
Anafilaxia
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo
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