Haplotypes of DXS10011 and DXS8377 in Guangdong Han individuals / 法医学杂志
Journal of Forensic Medicine
; (6): 207-209, 2006.
Article
em Zh
| WPRIM
| ID: wpr-983182
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To investigate genetic polymorphism of two X chromosome specific STR: DXS10011 and DXS8377 in male samples from Guangdong Han population.@*METHODS@#The DNA samples were amplified by PCR and analyzed by polyacrylamide gel electrophoresis followed by silver staining.@*RESULTS@#Among 113 samples, 20 alleles were found for DXS1011 and 12 alleles for DXS8377. Also, 72 DXS10011-DXS8377 haplotypes were shown. The most common haplotypes only occurred three times. When only female children were tested in motherless case, the exclusion probability of paternity was 0.9588 for DXS10011-DXS8377 haplotypes. Investigations in 83 family trios with female children and 29 pedigrees with two children suggested a co-dominant X-linked inheritance; mutations were not found.@*CONCLUSION@#Our data indicate that DXS10011 and DXS8377 are highly informative X chromosome markers for complicated kinship analysis.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Paternidade
/
Polimorfismo Genético
/
Haplótipos
/
DNA
/
China
/
Reação em Cadeia da Polimerase
/
Sequências de Repetição em Tandem
/
Cromossomos Humanos X
/
Ciências Forenses
/
Povo Asiático
Limite:
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Ano de publicação:
2006
Tipo de documento:
Article