Expression of EDA-fibronectin in injured human skin fibroblast and its potential application in estimation of wound healing / 法医学杂志

ABSTRACT

OBJECTIVE@#[corrected] To study the expression of EDA-FN variant in injured human skin fibroblast and its relation to wound healing.@*METHODS@#Human skin fibroblast cells were separated from human skin and cultured and monoclonal antibody to fibronectin [IST-9] was applied to amplify target segments.@*RESULTS@#Trace amount of EDA-FN was detected in the culture cells. The expression was increased within 8 hours after the injury.@*CONCLUSIONS@#The expression of EDA-FN would be an ideal marker for estimation of wound healing