Apoptosis in rat corpus cavernous penis after neruotomy of bilateral dorsal nerve of penis and/or cavernous nerve / 法医学杂志
Journal of Forensic Medicine
;
(6): 97-101, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-983360
ABSTRACT
OBJECTIVE@#To observe the apoptosis in penile corpus cavernous after neurotomy.@*METHODS@#After neurotomy, 78 SD rats were randomly assigned to experimental and normal control groups at day 1, 2, 4, 8, 16, and 32 time point. The quality was measured by DNA Ladder and the quantitation was measured by TUNEL. The location of apoptosis was detected by dual stained with immunohistochemistry and TUNEL.@*RESULTS@#After transaction of cavernous nerve, dorsal never, and both nerves, the apoptosis in experimental and control group showed a statistically significant difference (P<0.0046); however there was no statistically significant difference after bilateral dorsal nerve transaction alone (P>0.0046). There was a statistically significant difference in apoptosis between cavernous smooth muscle cell and endothelial cell groups (P<0.05).@*CONCLUSION@#Cavernous nerve transection induces apoptosis in smooth muscle cells of the rat penis, but nor does dorsal nerve transaction alone. There is no statistically significant difference in apoptosis between cavernous nerve injury alone and combination injuries of cavernous nerve and dorsal nerve.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pênis
/
Ereção Peniana
/
Distribuição Aleatória
/
Ratos Sprague-Dawley
/
Apoptose
/
Denervação Autônoma
/
Traumatismos dos Nervos Periféricos
/
Músculo Liso
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo
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