Determination of Cr, Cd, As, Tl and Pb in blood by inductively coupled plasma mass spectrometry / 法医学杂志

ABSTRACT

OBJECTIVE@#To establish an inductively coupled plasma mass spectrometry (ICP-MS) method for determination of Cr, Cd, As, Tl and Pb in blood.@*METHODS@#The samples were digested by microwave digestion instrument. ICP-MS was applied to determine Cr, Cd, As, Tl and Pb in blood by using 115In as an internal standard.@*RESULTS@#The limits of detection were in the range of 0.00001-0.00249 microg/L. The accuracy of the method ranged from 90.1% to 110.7% and the precision ranged from 4.0% to 7.9%.@*CONCLUSION@#The method is accurate and rapid with superior sensitivity and linear range. It could be used in the poisoning cases caused by Cr, Cd, As, Tl and Pb.